Publications


RECENT PUBLICATIONS RELEVANT TO OUR TECHNOLOGIES 

1. Jans H-S et al. Radiation Dosimetry of Theragnostic Pairs for Isotopes of Iodine. Pharmaceutics. 14,  1655. https://doi.org/10.3390/pharmaceutics14081655 (2022). 

2. Rashed F-B et al. Cellular mechanism of action of 2-nitroimidzoles as hypoxia-selective therapeutic  agents. Redox Biology. https://doi.org/10.1016/j.redox.2022.102300 (2022). 

3. Diaz-Dussan D et al. Optimized Carbohydrate-Based Nanogel Formulation to Sensitize Hypoxic  Tumors. Mol Pharmaceutics. https://doi.org/10.1021/acs.molpharmaceut.3c00101 (2023). 

4. Rashed F-B et al. Identification of Proteins and Cellular Pathways Targeted by 2-Nitroimidazole  Hypoxic Cytotoxins. Redox Biology. Vol 41. https://doi.org/10.1016/j.redox.2021.101905. (May  2021). 

5. Elsaidi RH et al. A simple computational tool for accurate, quantitative prediction of one–electron  reduction potentials of hypoxia–activated tirapazamine analogues. J Pharm Pharmaceutical Sci.  23(1), 231-242. doi.org/10.18433/jpps30602 (2020)

6. Diaz-Dussan D et al. Glyco-Nanomedicines and Their Applications in Cancer Treatment. Comprehensive Glycoscience, 2nd edition. https://doi.org/10.1016/B978-0-12-819475-1.00066-3 (2020). 

7. Elsaidi RH et al. Putative electron-affinic radiosensitizers and markers of hypoxic tissue: Synthesis  and preliminary in vitro biological characterization of C3-amino-substituted benzotriazine dioxides  (BTDOs). Euro J Med Chem. doi.org/10.1016/j.ejmech.2019.01.009 (2019). 

8. Elsaidi RH et al. Development of [131I]I-EOE-TPZ and [131I]I-EOE-TPZMO: Novel Tirapazamine  (TPZ)-Based Radioiodinated Pharmaceuticals for Application in Theranostic Management of  Hypoxia. Pharmaceuticals 2019, 12, 3; doi:10.3390/ph12010003 (2019). 

9. Sun W et al. Synthesis of [18F]FAZA using Nosyl and Iodo Precursors for Nucleophilic  Radiofluorination. Curr Radiopharmaceuticals. 12:49-57. doi:  10.2174/1874471011666181019105947 (2019)

10. Peng, Y-Y et al. Tumor Microenvironment-Regulated Redox Responsive Cationic Galactose-Based  Hyperbranched Polymers for SiRNA Delivery. Bioconjug Chem. 30 (2), 405–412.  https://doi.org/10.1021/acs.bioconjchem.8b00785 (2019). 

11. Jans H-S et al. Positron Emission Tomography (PET) and Pharmacokinetics: Classical Blood  Sampling Versus Image-Derived Analysis of [18F]FAZA and [18F]FDG in a Murine Tumor Bearing  Model. J Pharm Pharmaceutical Sci (www.cspsCanada.org) 21:32s – 47s.  doi: 10.18433/jpps29788 (2018).